12.23.2010
12.22.2010
Stem cell therapy to heal a broken heart
Flu... there's a shot for that. Broken bone...there's a shot for that too
Today, a broken hip usually means surgery and extensive rehab. But what if all you needed was an injection and a shorter recovery period? That's the vision that inspires Thomas Webster, an associate professor of engineering at Brown University.
Webster has developed a nanomaterial that quickly solidifies at body temperature into a bone-like substance. This week, Brown announced a deal with medical device maker Audax Medical of Littleton, Massachusetts, to further develop the material and launch trials in animals.
Skip the biopsy...ask for laser beams instead
People helping computers process information for a change
11.24.2010
Essay writing turns into facebook browsing turns into youtube watching...
11.22.2010
Yay alma mater...UBC research actually matters!
11.18.2010
Turning skin into blood...21st century alchemy
Earthquake repair 101
11.16.2010
Muscle regeneration just needs some guidance in the right direction
11.12.2010
11.10.2010
Who put the microchip in my benadryl?
11.04.2010
Thinking about replacing your home's windows? Go green with solar-powered ones!
10.28.2010
10.19.2010
A Long-Lasting Universal Flu Vaccine
While vaccines for other infections can create immunity that lasts for decades, the flu virus has proved a more challenging adversary. Because the human immune system is so adept at recognizing it, the virus has evolved the ability to modify its most recognizable protein--called hemagglutinin--from year to year. So every year, six months prior to flu season, the U.S. Food and Drug Administration devises the country's annual vaccine according to its best guess for which strains will be most virulent. And every year, we need another flu shot.
Palese's experimental vaccine, however, targets a part of the hemagglutinin protein that remains relatively stable over time, enabling its broad immunizing effects.
Making a Genome Quickly from Scratch
10.01.2010
Reefer Gladness
9.24.2010
9.21.2010
Yet another step towards a television free world
A new one-cubic-centimeter projector head that can be integrated into a portable computer or mobile telephone has been developed by Lemoptix, a spin-off of Ecole Polytechnique Federale de Lausanne (EPFL), and the Maher Kayal Laboratory.
Test tube babies are so 2009
8.25.2010
8.15.2010
Weekend Chuckles
8.06.2010
Screw polysporin, give me some fibronectin for my owie
Protein pattern: This computer rendering shows ripples on fabric made from protein. Such fabrics could be used as scaffolds for growing organs. Credit: ACS/ Nano Letters |
http://www.technologyreview.com/biomedicine/25918/?nlid=3315
8.04.2010
TV Reporter Bloopers
Top 10 funniest news reporter bloopers
8.03.2010
I hope none of these guys are getting behind the wheel of a car
Good for a chuckle
8.02.2010
Worse than an oil spill...farming
As if the BP oil spill didn't cause enough damage to the coastal areas of the Gulf of Mexico, large amounts of nitrogen and other nutrients from midwest agricultural lands has washed down the Mississippi river and entered the Gulf.
So...what are the repercussions of this?
The abundance of nutrients causes a dramatic increase in the plant life initially (e.g. algal bloom) but then creates what is known as a 'hypoxic zone' or 'dead zone' as all the oxygen dissolved in the water gets used up by the photosynthesizing plants. This has huge ramifications for the animal life in those areas, and could be costlier to the ecosystem and the Gulf fishing economy than the BP oil spill.
7.31.2010
The end of tv
7.28.2010
Generation Kill by Evan Wright
My rating: 4 of 5 stars
I started this book after having watched the HBO mini-series of the same name produced by the same guys who wrote 'The Wire'. There are a lot of characters introduced and missions undertaken by the First Recon Marines during the initial assault of Iraq and it was really helpful for me to picture the real-life men in the book with the actors who portray them so accurately.
View all my reviews >>
7.27.2010
Have humans evolved to love medicine?
Neurobiology and immunobiology of the placebo effect. Adapted from Pacheco-Lopez et al (2006).
Why do we love medicines so much?
- EMBO reports (2010) 11, 572 - 578
- doi:10.1038/embor.2010.108
Algae to energy, seems simple enough
Schematic drawing of an algae farm for the production of biofuels.
The tide turns towards microalgae
Philip Hunter- EMBO reports (2010) 11, 583 - 586
- doi:10.1038/embor.2010.103
7.21.2010
It's like the 70's all over again, tree-hugging hippies working with military veterans
-Really interesting article written by Bryan Walsh for TIME.com connecting the wars raging in The Middle East with the BP oil spill in the Gulf of Mexico.
Wait a second, can you repeat that?...Did you say the atmosphere almost collapsed?
You mean stuff actually gets done at the Pentagon
http://www.physorg.com/news198221258.html
So that's why the Arizona desert is so damn hot...
http://www.physorg.com/news198434180.html
Radio waves & vibrations... what's the first thing that comes to mind? Batteries, duh
Vibration-powered Generators Replace AA, AAA Batteries
7.20.2010
Petition to my senators
note: I've recently read magazine articles in The Atlantic (Here Comes the Neighborhood) and Time (All Aboard) about the environmental and economic benefits in building light-rail networks connecting suburbs to urban centres and utilizing high-speed trains for potential daily commuters.
Here is a bit of that petition:
For the past three months oil has gushed into our Gulf, yet the Senate has not taken up a comprehensive energy bill that will hold polluters accountable and create a clean, sustainable energy plan that breaks our addiction to oil and other dirty fuels.
-- Develop and support a comprehensive clean energy policy at home -- wind, solar, geothermal and other sustainable energy that we can use this decade. Provide incentives and mandates for increased production of clean, safe energy.
-- Hold polluters fully accountable and require them to meet reasonable targets to reduce their greenhouse gas pollution -- or be penalized.
-- Prioritize energy efficiency. The cheapest form of energy is energy that's not used. Incentives for weatherization, strong building energy codes and appliance standards improve our standard of living while cutting costs for consumers and reducing the need for more power plants.
*-- Create jobs and Connect the country. The development of a high-speed rail network connecting the major economic centres of the country would:
A) Reduce the high carbon emissions of the current transportation sector (I'll get a little shut-eye on my bed for the overnight train from Seattle to New York City),
F) 0%, the chances of any emergency landings in the Hudson River due to Migrating Canadian Geese(http://www.msnbc.msn.com/id/28678669/)
H) It's win, win, win for The Economy, The Global Warming Crisis, and Joe The Average Railroad Worker.
*My personalized message
The Gulf oil-spill nightmare is a national tragedy, but it also can be a catalyst for changing how America develops and uses energy. For too long Washington has ignored our growing problem of dependence on foreign oil and dirty energy production. The time has come to take up and pass a comprehensive energy bill now and I urge you as my Senator to do all you can to make that happen.
Sincerely,
[Your Name]
[Your Address]
[City, State ZIP]
7.16.2010
Ever wonder how to dig a hole at the bottom of the ocean...
The video is a presentation from a Shell engineer describing how exactly deep sea oil drilling works and why their system is safer than BP's. It's pretty long but you can skip ahead to around 13:00 where he describes how this concept is humanly possible and why BP sucks.
http://dotearth.blogs.nytimes.com/2010/07/15/bp-shell-and-the-design-of-deep-wells/
7.15.2010
7.13.2010
A chemical to make brain cells grow: Mental decline thwarted in aging rats
LOL
Quotes of things people actually said in U.S. courts from a book titled, Disorder in the American Courts, published by court reporters.
ATTORNEY: Are you sexually active?
WITNESS: No, I just lie there.
ATTORNEY: This myasthenia gravis, does it affect your memory at all?
WITNESS: Yes.
ATTORNEY: And in what ways does it affect your memory?
WITNESS: I forget.
ATTORNEY: You forget? Can you give us an example of something you forgot?
ATTORNEY: Do you know if your daughter has ever been involved in voodoo?
WITNESS: We both do.
ATTORNEY: Voodoo?
WITNESS: We do.
ATTORNEY: You do?
WITNESS: Yes, voodoo.
ATTORNEY: Now doctor, isn't it true that when a person dies in his sleep, he doesn't know about it until the next morning?
WITNESS: Did you actually pass the bar exam?
ATTORNEY: The youngest son, the twenty-year-old, how old is he?
WITNESS: He's twenty, much like your IQ.
ATTORNEY: She had three children, right?
WITNESS: Yes.
ATTORNEY: How many were boys?
WITNESS: None.
ATTORNEY: Were there any girls?
WITNESS: Your Honor, I think I need a different attorney. Can I get a new attorney?
ATTORNEY: How was your first marriage terminated?
WITNESS: By death.
ATTORNEY: And by whose death was it terminated?
WITNESS: Take a guess.
ATTORNEY: Can you describe the individual?
WITNESS: He was about 20, medium height, and had a beard.
ATTORNEY: Was this a male or a female?
WITNESS: Unless the Circus was in town, I'm going with male.
ATTORNEY: Doctor, how many of your autopsies have you performed on dead people?
WITNESS: All of them. The live ones put up too much of a fight.
ATTORNEY: ALL your responses MUST be oral, OK?
What school did you go to?
WITNESS: Oral.
ATTORNEY: Do you recall the time that you examined the body?
WITNESS: The autopsy started around 8:30 p.m.
ATTORNEY: And Mr. Denton was dead at the time?
WITNESS: If not, he was by the time I finished.
ATTORNEY: Are you qualified to give a urine sample?
WITNESS: Are you qualified to ask that question?
ATTORNEY: Doctor, before you performed the autopsy, did you check for a pulse?
WITNESS: No.
ATTORNEY: Did you check for blood pressure?
WITNESS: No.
ATTORNEY: Did you check for breathing?
WITNESS: No.
ATTORNEY: So, then it is possible that the patient was alive when you began the autopsy?
WITNESS: No.
ATTORNEY: How can you be so sure, Doctor?
WITNESS: Because his brain was sitting on my desk in a jar.
ATTORNEY: I see, but could the patient have still been alive, nevertheless?
WITNESS: Yes, it is possible that he could have been alive and practicing law.
A Friendly Rivalry
A Kiwi ventriloquist visiting Australia walks into a small village and sees a local sitting on his veranda patting his dog.
He figures he'll have a little fun, so he says to the local, “G'day, mind if I talk to your dog?”
Villager: “The dog doesn't talk, you stupid Kiwi.”
Ventriloquist: “Hello dog, how's it going, mate?”
Dog: “Yeah, doin' all right.”
Aussie (look of extreme shock)
Ventriloquist: “Is this villager your owner?” (pointing at the villager)
Dog: “Yep.”
Ventriloquist: “How does he treat you?”
Dog: “Yeah, real good. He walks me twice a day, feeds me great food, and takes me to the lake now and again to play.”
Aussie: (look of utter disbelief)
Ventriloquist: “Mind if I talk to your horse?”
Aussie: “Uh, the horse doesn't talk either... I think.”
Ventriloquist: “Hey horse, how's it going?”
Horse: “Cool.”
Aussie: (absolutely dumbfounded)
Ventriloquist: “Is this your owner?” (Pointing at the villager)
Horse: ”Yep.”
Ventriloquist: “How does he treat you?”
Horse: ”Pretty good, thanks for asking. He rides me regularly, brushes me down often, and keeps me in the shed to protect me from the elements.”
Aussie: (total look of amazement)
Ventriloquist: “Mind if I talk to your sheep?”
Aussie (in a panic): “The sheep's a compulsive liar.”
http://www.caseyresearch.com/displayCdd.php?id=479
7.09.2010
7.08.2010
My rating: 4 of 5 stars
Gladwell uses several stories to support his hypothesis that a person's innate abilities do not solely determine their success in life. He argues that it is also, if not more, important to understand the situations and circumstances throughout a person's life to pick out a true "Outlier."
View all my reviews >>
Battling global warming...with whale poop
6.07.2010
Come on med schools, pick up the slack
6.03.2010
Technology's smallest microscope, medicine's biggest ally
Engineer invents world's smallest, lightest telemedicine microscope
-Telemedicine involves performing medical tests in the field and requires portable tools in a resource-limited environment and integration into a medical network e.g. hospital or central lab.
http://www.physorg.com/news191170981.html
Quantum mechanics drives photosynthesis - you lost me at quantum
-Everyone has heard of photosynthesis - a process used by green plants to convert sunlight into electrochemical energy at an efficiency of nearly 100%.
-Although the overall pathway and major players are known for this process, the nitty-gritty details have eluded scientists, until now.
-Physical chemists at UC Berkeley observed 'entanglement' (a distinctive property of quantum mechanical systems) in the light harvesting complex in plants.
-Importance: huge step towards developing (a) artificial photosynthesis systems as renewable, non-polluting electrical energy sources and (b) quantum-based technologies e.g. quantum computers which are potentially thousands of times faster than conventional computers.
http://newscenter.lbl.gov/feature-stories/2010/05/10/untangling-quantum-entanglement/
It's about time windmills grew sea-legs
6.02.2010
Nanofoods - coming soon to a grocery store near you
http://food.change.org/blog/view/are_nanofoods_sustainable
6.01.2010
Low battery? Just plug it in...to yourself
How to make a cell for dummies
The scientists who created a synthetic variant are in debt to nature, time and billions of years of evolution.
Just another day in the life of a carbon nanotube
-One defensive strategy in the human immune system utilizes T cells, which are able to detect bad stuff in the body, replicate in lymph nodes, and then induce a strong immune response.
-Tumor cells are able to survive because they prevent tumor-specific T cells from replicating and therefore suppress any immune response.
-A technique called 'Adoptive Immunotherapy' is a treatment option, where patient's blood is drawn and T cells are stimulated and replicated in the lab before being transferred back into the patient.
-A major drawback right now is that it can take several weeks until sufficient T cells are produced.
-Yale scientists have found that carbon nanotubes mimic lymph nodes in the lab and reduce the time to produce enough tumor-fighting T cells by 1/3.
-All that is needed now is find an efficient way of removing the carbon nanotubes before re-injecting the T cells into the patient.
5.28.2010
5.25.2010
Goodbye LOST
http://www.hitfix.com/blogs/whats-alan-watching/posts/lost-the-end-see-you-in-the-other-life-brother#
TV critic Alan Sepinwall's review of the series finale.
5.24.2010
One small step for man, One giant leap for cancer treatment
-'DNA -> RNA -> Protein' is the central dogma of genetics.
-A good way for me to remember complex scientific concepts is to put them in context with something simpler that I understand.
-For me the best context for this genetic concept is comparing it to opening a zip file on the computer.
-Say you have a zip file (DNA). You cannot simply open the zip file, because it is only useful for storage.
-In order to open the zip file you must first unzip it (transcription) into a readable file (RNA).
-Now, when you try and open the unzipped file (RNA) it results in something usable such as a word document, pdf, or mp3 (protein).
-Most anticancer drugs target certain proteins unique to the growth and survival of tumor cells.
-These therapeutics have some limitations because of the 3-D shapes of proteins and the possibility of mutations which 'hide' the protein from the drug without changing the protein's use for the cell.
-A new approach using small interfering RNAs (siRNAs) targets a type of RNA in the cell called messenger RNA (mRNA).
-Unlike protein, mRNA is linear in shape (no bends/folds to hide itself) and has fewer potential mutations.
-This therapy is very exciting because it allows for the indirect targeting of virtually every protein.
-A major hurdle of this therapy (other than getting the siRNA into the cell is targeting only the tumor cell(s).
-Solution = packing the siRNA into nanoparticles which bind only to cancerous cells, then release the siRNA into the bound tumor cell.
-Most importantly, this combined treatment was found to be effective in a human patient during a phase I clinical trial.
-This therapy is being developed for treating cancer, but I can see it being utilized for treating nearly every disease.
5.21.2010
Nuclear fusion power - the ultimate clean energy
(PhysOrg.com) -- Imagine if you could generate electricity using nuclear power that emitted no radioactivity: it would be the answer to the world's dream of finding a clean, sustainable energy source.
Solar cells - I think they can, I think they can
Thanks to two technologies developed by Professor Benoit Marsan and his team at the Universite du Quebec a Montreal (UQAM) Chemistry Department, the scientific and commercial future of solar cells could be totally transformed. Professor Marsan has come up with solutions for two problems that, for the last twenty years, have been hampering the development of efficient and affordable solar cells.
http://www.er.uqam.ca/nobel/dep_chim/rindex.php?dossierprof=prof&pagehtm=marsan.htm
How many scientists does it take to replace a light bulb? None, cause it never burns out
(PhysOrg.com) -- Light bulbs that last 100 years and fill rooms with brilliant ambiance may become a reality sooner rather than later, thanks to a National Renewable Energy Laboratory discovery.
Can you hold your breath forever?
(PhysOrg.com) -- Oxygen may not be the staple of modern complex life that scientists once thought. Until now, the only life forms known to live exclusively in anoxic conditions were viruses, bacteria and Archaea. But in a new study, scientists have discovered three new multicellular marine species that appear to have never lived in aerobic conditions, and never metabolized oxygen.
Putting oil profits to good use
(PhysOrg.com) -- A new eco-city being built in the United Arab Emirates (UAE), Masdar City, will be the world’s first clean technology city, relying entirely on renewable energy sources, and being free of cars, skyscrapers and waste.
'Organic Electronics' coming soon to a Whole Foods near you
(PhysOrg.com) -- A new technique developed by Princeton University engineers for producing electricity-conducting plastics could dramatically lower the cost of manufacturing solar panels.
Bacteria don't like getting poked
ScienceDaily (2010-03-15) -- For two decades, scientists have been pursuing a potential new way to treat bacterial infections, using naturally occurring proteins known as antimicrobial peptides (AMPs). Now, scientists have recorded the first microscopic images showing the deadly effects of AMPs, most of which kill by poking holes in bacterial cell membranes.
I love gooooold. But cancer sure doesn't
ScienceDaily (2010-03-16)
-"Magic Bullets" are highly targeted medical treatments which are the ultimate goal for drug development.
-Cancer has evaded these so-called bullets because of drastic changes in tumors between (1) different stages of cancer development, (2) different organs/tissues of the body, and (3) different patients.
-A new treatment developed at Washington University in St. Louis may be able to target cancer cells and selectively kill them with minimal damage to healthy cells.
-The technique is called 'Photothermal Therapy' and involves injecting gold nanocages into a patient's bloodstream (gold is inert and therefore nontoxic at low levels).
-Some of these 'golden bullet' nanocages accumulate at the tumor site (~6%) through leaky blood vessels (a commonality between tumor).
-A laser is then shone on the tumor site and the nanocages present convert light into heat which leads to the death of the tumor cells and has little/no effect on the surrounding healthy cells.
-This treatment was shown to work in a mouse model, but with the way things are currently for translating developments from the lab-to-clinic, this technology should be available in 100 years or so.
-This treatment isn't perfect yet, more research has begun on actively targeting cancer cells so fewer particles need to be injected, but is a huge tool in treating cancer which could be effective right now!
Frogs, foam and fuel: Solar energy converted to sugars
ScienceDaily (2010-03-17) -- In natural photosynthesis, plants take in solar energy and carbon dioxide and then convert it to oxygen and sugars. The oxygen is released to the air and the sugars are dispersed throughout the plant -- like that sweet corn we look for in the summer. Unfortunately, the allocation of light energy into products we use is not as efficient as we would like. Now engineering researchers are doing something about that.
Splitting water into hydrogen and oxygen, sort of like the Moses of chemistry
ScienceDaily (2010-03-18) -- Chemists have developed the most potent homogeneous catalyst known for water oxidation, considered a crucial component for generating clean hydrogen fuel using only water and sunlight.
5.20.2010
Primary care doctors - an endangered species
Laser-ignited nanoparticles, oh the possibilites
-By hitting carbon nanoparticles with a relatively weak laser, University of Florida engineers could release their stored energy causing light, heat, or burning depending on the conditions.
-Potential uses:
- Identification and specific-killing of cancer cells without damaging normal cells.
- Ignition of powerful explosives used by mining, tunneling, or demolition crews instead of time-consuming and expensive electrical lines currently used.
- Replacing traditional sparkplugs for more efficient gasoline burning in cars.
- More than a dozen other potential applications.